In vitro activities of Citrus medica L. cv. Diamante (Diamante citron) relevant to treatment of diabetes and Alzheimer's disease
Identifieur interne : 000778 ( Main/Exploration ); précédent : 000777; suivant : 000779In vitro activities of Citrus medica L. cv. Diamante (Diamante citron) relevant to treatment of diabetes and Alzheimer's disease
Auteurs : Filomena Conforti [Italie] ; Giancarlo Antonio Statti [Italie] ; Rosa Tundis [Italie] ; Monica Rosa Loizzo [Italie] ; Francesco Menichini [Italie]Source :
- Phytotherapy Research [ 0951-418X ] ; 2007-05.
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Abstract
The present study showed for the first time the in vitro properties (antioxidant, hypoglycaemic and anticholinesterase) of Citrus medica L. cv. Diamante which belongs to the Rutaceae family. The n‐hexane extract of Diamante citron peel is characterized by the presence of monoterpenes and sesquiterpenes. The most abundant constituents were two monoterpenes: limonene and γ‐terpinene. The extract showed significant antioxidant activity that was carried out using different assays (DPPH test, β‐carotene bleaching test and bovine brain peroxidation assay). Oxidative damage, caused by the action of free radicals, may initiate and promote the progression of a number of chronic diseases, including diabetes and Alzheimer's disease. Diamante citron peel extract showed hypoglycaemic activity and an anticholinesterase effect. Copyright © 2007 John Wiley & Sons, Ltd.
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DOI: 10.1002/ptr.2077
Affiliations:
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Res.</title><idno type="ISSN">0951-418X</idno><idno type="eISSN">1099-1573</idno><imprint><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="2007-05">2007-05</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="427">427</biblScope><biblScope unit="page" to="433">433</biblScope></imprint><idno type="ISSN">0951-418X</idno></series><idno type="istex">870B769197CAFBCB3CDAD9522E8340CEC39C683A</idno><idno type="DOI">10.1002/ptr.2077</idno><idno type="ArticleID">PTR2077</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0951-418X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alzheimer's disease</term><term>Citrus medica L. cv. Diamante</term><term>Rutaceae</term><term>antioxidant and hypoglycaemic activities</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The present study showed for the first time the in vitro properties (antioxidant, hypoglycaemic and anticholinesterase) of Citrus medica L. cv. Diamante which belongs to the Rutaceae family. The n‐hexane extract of Diamante citron peel is characterized by the presence of monoterpenes and sesquiterpenes. The most abundant constituents were two monoterpenes: limonene and γ‐terpinene. The extract showed significant antioxidant activity that was carried out using different assays (DPPH test, β‐carotene bleaching test and bovine brain peroxidation assay). Oxidative damage, caused by the action of free radicals, may initiate and promote the progression of a number of chronic diseases, including diabetes and Alzheimer's disease. Diamante citron peel extract showed hypoglycaemic activity and an anticholinesterase effect. Copyright © 2007 John Wiley & Sons, Ltd.</div></front></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Conforti, Filomena" sort="Conforti, Filomena" uniqKey="Conforti F" first="Filomena" last="Conforti">Filomena Conforti</name></noRegion><name sortKey="Loizzo, Monica Rosa" sort="Loizzo, Monica Rosa" uniqKey="Loizzo M" first="Monica Rosa" last="Loizzo">Monica Rosa Loizzo</name><name sortKey="Menichini, Francesco" sort="Menichini, Francesco" uniqKey="Menichini F" first="Francesco" last="Menichini">Francesco Menichini</name><name sortKey="Statti, Giancarlo Antonio" sort="Statti, Giancarlo Antonio" uniqKey="Statti G" first="Giancarlo Antonio" last="Statti">Giancarlo Antonio Statti</name><name sortKey="Tundis, Rosa" sort="Tundis, Rosa" uniqKey="Tundis R" first="Rosa" last="Tundis">Rosa Tundis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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